diff --git a/docs/release-notes/version-2.10.md b/docs/release-notes/version-2.10.md
index 1580b9077..ca53d0cbf 100644
--- a/docs/release-notes/version-2.10.md
+++ b/docs/release-notes/version-2.10.md
@@ -17,6 +17,7 @@
 * [#5486](https://github.com/netbox-community/netbox/issues/5486) - Optimize retrieval of config context data for device/VM REST API views
 * [#5487](https://github.com/netbox-community/netbox/issues/5487) - Support filtering rack type/width with multiple values
 * [#5498](https://github.com/netbox-community/netbox/issues/5498) - Fix filtering rack reservations by username
+* [#5499](https://github.com/netbox-community/netbox/issues/5499) - Fix filtering of displayed device/VM interfaces by regex
 
 ---
 
diff --git a/netbox/dcim/tables/devices.py b/netbox/dcim/tables/devices.py
index 536be66d9..663206505 100644
--- a/netbox/dcim/tables/devices.py
+++ b/netbox/dcim/tables/devices.py
@@ -447,7 +447,8 @@ class DeviceInterfaceTable(InterfaceTable):
             'connection', 'actions',
         )
         row_attrs = {
-            'class': lambda record: record.cable.get_status_class() if record.cable else ''
+            'class': lambda record: record.cable.get_status_class() if record.cable else '',
+            'data-name': lambda record: record.name,
         }
 
 
diff --git a/netbox/project-static/js/interface_filtering.js b/netbox/project-static/js/interface_filtering.js
index fecb156f4..51ac70198 100644
--- a/netbox/project-static/js/interface_filtering.js
+++ b/netbox/project-static/js/interface_filtering.js
@@ -1,11 +1,10 @@
 // Inteface filtering
 $('input.interface-filter').on('input', function() {
-    var filter = new RegExp(this.value);
-    var interface;
+    let filter = new RegExp(this.value);
+    let interface;
 
     for (interface of $('table > tbody > tr')) {
-        // Slice off 'interface_' at the start of the ID
-        if (filter.test(interface.id.slice(10))) {
+        if (filter.test(interface.getAttribute('data-name'))) {
             // Match the toggle in case the filter now matches the interface
             $(interface).find('input:checkbox[name=pk]').prop('checked', $('input.toggle').prop('checked'));
             $(interface).show();
diff --git a/netbox/virtualization/tables.py b/netbox/virtualization/tables.py
index 97e1d6e36..34a070623 100644
--- a/netbox/virtualization/tables.py
+++ b/netbox/virtualization/tables.py
@@ -183,3 +183,6 @@ class VirtualMachineVMInterfaceTable(VMInterfaceTable):
         default_columns = (
             'pk', 'name', 'enabled', 'mac_address', 'mtu', 'mode', 'description', 'ip_addresses', 'actions',
         )
+        row_attrs = {
+            'data-name': lambda record: record.name,
+        }